Two patients ask me this question, and they ask it from opposite directions. The first has slept six hours a night for twenty years and feels fine. He wants to know whether the warnings apply to him. The second sleeps nine hours, wakes up tired anyway, and wants to know what is wrong. Until recently the honest answer was that sleep research mostly measured how people felt, or how long they lived, without much in between. A study published in Nature this year measured somethin

Several patients have forwarded me the same kind of message over the past two weeks. An email from a wellness clinic. A post from a trainer. A headline asking, in one form or another, did the FDA legalize peptides. Something did happen in late July. It is worth walking through carefully, because the event and the way it was described are not quite the same thing. What Happened on July 23 and 24 The FDA's Pharmacy Compounding Advisory Committee met over two days to consider se

A patient came in recently with a printed menu from a wellness clinic. Fourteen peptides, each with a short description, each priced by the month. She wanted to know what was known about them. That turned out to be a longer conversation than either of us expected, because the list combined compounds that have almost nothing in common. Some have been studied in tens of thousands of people. For others, the human research has not really begun. The word "peptide" was the only thi

You forgot a name you have known for years. You walked into the kitchen and could not remember why you went in. A word sat on the edge of your tongue and refused to come. And underneath it all was a quieter thought. Is this how it starts. If you have started to worry about memory loss, you are not alone, and you are not necessarily in trouble. I hear this concern in my office more than almost any other, and most of the time the person across from me is fine. But most of the t

By Dr. Jeffrey Shukhman | White Olive Direct Personalized Care You have probably seen it by now. NAD IV infusions at wellness clinics. NMN capsules on longevity podcasts. NR powders being sold next to protein shakes. The marketing is confident. The price tags are significant. And the promises, "more energy, slower aging, better brain function, longer life,"sound exactly like what most people want to hear. So, do NAD supplements actually work? I went through the clinical resea